Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D01UWZ
|
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| Former ID |
DIB019359
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| Drug Name |
compound 22c
|
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| Drug Type |
Small molecular drug
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C35H46ClN5O4
|
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| InChI |
InChI=1S/C35H45N5O4.ClH/c1-6-7-15-40-33-27(13-9-14-37-33)30(25-11-8-12-26(20-25)44-17-10-16-41)32(34(40)42)39-35(43)38-31-28(22(2)3)18-24(21-36)19-29(31)23(4)5;/h8-9,11-14,18-20,22-23,41H,6-7,10,15-17,21,36H2,1-5H3,(H2,38,39,43);1H
|
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| InChIKey |
OXTVBHDILDPYAS-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Acetyl-CoA acetyltransferase, mitochondrial | Target Info | Inhibitor | [527814] | |
| KEGG Pathway | Fatty acid degradation | ||||
| Synthesis and degradation of ketone bodies | |||||
| Valine, leucine and isoleucine degradation | |||||
| Lysine degradation | |||||
| Tryptophan metabolism | |||||
| Pyruvate metabolism | |||||
| Glyoxylate and dicarboxylate metabolism | |||||
| Propanoate metabolism | |||||
| Butanoate metabolism | |||||
| Terpenoid backbone biosynthesis | |||||
| Metabolic pathways | |||||
| Biosynthesis of antibiotics | |||||
| Carbon metabolism | |||||
| Fatty acid metabolism | |||||
| NetPath Pathway | Leptin Signaling Pathway | ||||
| PANTHER Pathway | CCKR signaling map ST | ||||
| References | |||||
| Ref 527814 | Bioorg Med Chem Lett. 2006 Jan 1;16(1):44-8. Epub 2005 Oct 18.Synthesis and biological activity of novel 4-phenyl-1,8-naphthyridin-2(1H)-on-3-yl ureas: potent acyl-CoA:cholesterol acyltransferase inhibitor with improved aqueous solubility. | ||||
| Ref 541831 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6730). | ||||
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