Drug General Information
Drug ID	D02PSZ
Former ID	DPR000006
Drug Name	A-74498
Indication	Obesity [ICD9: 278; ICD10:E66]		Preclinical	[536122]
Company	Abbott
Structure		Download 2D MOL
Target and Pathway
Target(s)	Cholecystokinin receptor type A	Target Info	Agonist	[536122]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Insulin secretion
	Pancreatic secretion
Reactome	Peptide ligand-binding receptors
	G alpha (q) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 536122	Emerging drugs for obesity: linking novel biological mechanisms to pharmaceutical pipelines. Expert Opin Emerg Drugs. 2005 Aug;10(3):643-60.
Ref 536122	Emerging drugs for obesity: linking novel biological mechanisms to pharmaceutical pipelines. Expert Opin Emerg Drugs. 2005 Aug;10(3):643-60.

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