Drug Information
Drug General Information | |||||
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Drug ID |
D03RYY
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Former ID |
DIB020567
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Drug Name |
NPC-349
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Synonyms |
[D-Arg0,Hyp2,3,Thi5,8,D-Phe7]bradykinin; NPC 349
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [541845] | ||
Structure |
Download2D MOL |
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Formula |
C56H83N19O13S2
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InChI |
InChI=1S/C56H83N19O13S2/c57-35(13-4-17-66-53(60)61)45(80)71-38(14-5-18-67-54(62)63)50(85)74-20-6-15-42(74)44(79)34(16-19-68-55(64)65)56(52(87)88,43(78)28-70-47(82)39-24-31(77)27-69-39)75(49(84)37(59)26-33-12-8-22-90-33)51(86)40(23-30-9-2-1-3-10-30)72-48(83)41(29-76)73-46(81)36(58)25-32-11-7-21-89-32/h1-3,7-12,21-22,31,34-42,69,76-77H,4-6,13-20,23-29,57-59H2,(H,70,82)(H,71,80)(H,72,83)(H,73,81)(H,87,88)(H4,60,61,66)(H4,62,63,67)(H4,64,65,68)/t31-,34?,35-,36+,37+,38+,39+,40-,41+,42+,56-/m1/s1
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InChIKey |
MHBUKMPYIGAURU-WIDHDRDXSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | B2 bradykinin receptor | Target Info | Antagonist | [533983] | |
KEGG Pathway | Calcium signaling pathway | ||||
cGMP-PKG signaling pathway | |||||
Sphingolipid signaling pathway | |||||
Neuroactive ligand-receptor interaction | |||||
Complement and coagulation cascades | |||||
Inflammatory mediator regulation of TRP channels | |||||
Regulation of actin cytoskeleton | |||||
Endocrine and other factor-regulated calcium reabsorption | |||||
Chagas disease (American trypanosomiasis) | |||||
Pathways in cancer | |||||
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
Pathway Interaction Database | Direct p53 effectors | ||||
Validated transcriptional targets of deltaNp63 isoforms | |||||
References |
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