Drug Information

Drug General Information
Drug ID
D03YVQ
Former ID
DIB021077
Drug Name
TRAM-34
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539480]
Structure
Download
2D MOL
Formula
C22H17ClN2
InChI
InChI=1S/C22H17ClN2/c23-21-15-8-7-14-20(21)22(25-17-9-16-24-25,18-10-3-1-4-11-18)19-12-5-2-6-13-19/h1-17H
InChIKey
KBFUQFVFYYBHBT-UHFFFAOYSA-N
PubChem Compound ID
656734
PubChem Substance ID
854029, 9268120, 14925089, 29217667, 50111720, 57408414, 71825456, 75409114, 91616312, 103654538, 104121165, 109693504, 113528168, 117682952, 118049510, 134346051, 135651273, 135698750, 137018275, 139724138, 143295681, 152159547, 160839807, 162117177, 162249125, 162486666, 163402143, 164825256, 170558942, 174006257, 175424207, 185988345, 204428698, 210274869, 210280503, 223376400, 223442254, 223496591, 223556723, 226426227, 242068329, 243645457, 249741150, 249846675, 250177573, 250195072, 251899788, 252040542, 252156894, 252313183
Target and Pathway
Target(s) KCa3.1 Target Info Blocker (channel blocker) [526701]
References
Ref 539480(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2336).
Ref 526701Blockade of the intermediate-conductance calcium-activated potassium channel as a new therapeutic strategy for restenosis. Circulation. 2003 Sep 2;108(9):1119-25. Epub 2003 Aug 25.

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