Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D04ASH
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| Former ID |
DAP001446
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| Drug Name |
Leuprorelin acetate
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| Synonyms |
Acetic acid; Leuprolide acetate; Enantone (TN); Leuplin (TN); Leuprorelin acetate (JAN); Lupron (TN); 5-oxoPro-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-ProNHC2H5 dihydrate
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| Drug Type |
Small molecular drug
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| Indication | Prostate cancer [ICD9: 185; ICD10:C61] | Approved | [550527] | ||
| Company |
Takeda
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| Structure |
|
Download2D MOL |
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| Formula |
C61H88N16O14
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| Canonical SMILES |
CCNC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C<br />(CC(C)C)NC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CO)NC(=O)C(CC3=<br />CNC4=CC=CC=C43)NC(=O)C(CC5=CN=CN5)NC(=O)C6CCC(=O)N6.CC(<br />=O)O
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| InChI |
1S/C59H84N16O12.C2H4O2/c1-6-63-57(86)48-14-10-22-75(48)58(87)41(13-9-21-64-59(60)61)68-51(80)42(23-32(2)3)69-52(81)43(24-33(4)5)70-53(82)44(25-34-15-17-37(77)18-16-34)71-56(85)47(30-76)74-54(83)45(26-35-28-65-39-12-8-7-11-38(35)39)72-55(84)46(27-36-29-62-31-66-36)73-50(79)40-19-20-49(78)67-40;1-2(3)4/h7-8,11-12,15-18,28-29,31-33,40-48,65,76-77H,6,9-10,13-14,19-27,30H2,1-5H3,(H,62,66)(H,63,86)(H,67,78)(H,68,80)(H,69,81)(H,70,82)(H,71,85)(H,72,84)(H,73,79)(H,74,83)(H4,60,61,64);1H3,(H,3,4)
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| InChIKey |
RGLRXNKKBLIBQS-UHFFFAOYSA-N
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| CAS Number |
CAS 64-19-7
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| SuperDrug ATC ID |
L02AE02
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| Target and Pathway | |||||
| Target(s) | Gonadotropin-releasing hormone receptor | Target Info | Agonist | [551717] | |
| NetPath Pathway | IL1 Signaling Pathway | ||||
| IL2 Signaling Pathway | |||||
| References | |||||
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