TTD | Drug: D04IAF

Drug General Information
Drug ID	D04IAF
Former ID	DIB018114
Drug Name	(S)-FTY720-phosphate
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[542025]
Structure		Download 2D MOL
Formula	C19H34NO5P
InChI	InChI=1S/C19H34NO5P/c1-2-3-4-5-6-7-8-17-9-11-18(12-10-17)13-14-19(20,15-21)16-25-26(22,23)24/h9-12,21H,2-8,13-16,20H2,1H3,(H2,22,23,24)/t19-/m0/s1
InChIKey	LRFKWQGGENFBFO-IBGZPJMESA-N
PubChem Compound ID	11452022
PubChem Substance ID	16551051, 23592634, 42531014, 49846978, 76286953, 103460256, 162263607, 164841891, 178103575, 230213677, 252450992, 252463377
Target and Pathway
Target(s)	Sphingosine-1-phosphate receptor-3	Target Info	Agonist	[528529]
KEGG Pathway	Sphingolipid signaling pathway
KEGG Pathway	Neuroactive ligand-receptor interaction
Pathway Interaction Database	S1P3 pathway
Pathway Interaction Database	Sphingosine 1-phosphate (S1P) pathway
Reactome	G alpha (i) signalling events
Reactome	Lysosphingolipid and LPA receptors
WikiPathways	Signal Transduction of S1P Receptor
	Small Ligand GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 542025	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6996).
Ref 528529	A monoselective sphingosine-1-phosphate receptor-1 agonist prevents allograft rejection in a stringent rat heart transplantation model. Chem Biol. 2006 Nov;13(11):1227-34.

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Drug Information