Drug General Information
Drug ID	D04SOS
Former ID	DIB005390
Drug Name	BMS-181168
Synonyms	BMY-21502
Drug Type	Small molecular drug
Indication	Cognitive disorders [ICD9: 290-294, 294.0, 780.09, 780.9, 780.93; ICD10:F01-F07, F04, F05, R41.3]		Discontinued in Phase 2	[544848]
Company	Bristol-Myers Squibb Co
Structure		Download 2D MOL 3D MOL
Formula	C15H19F3N4O
Canonical SMILES	n1c(C(F)(F)F)nccc1N1CCC(CN2C(=O)CCC2)CC1
CAS Number	CAS 123259-91-6
PubChem Compound ID	129930
Target and Pathway
Target(s)	Acetylcholine receptor	Target Info	Modulator	[534294]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Muscarinic acetylcholine receptors
	Acetylcholine regulates insulin secretion
	Highly sodium permeable acetylcholine nicotinic receptors
	Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
WikiPathways	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
References
Ref 544848	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001318)
Ref 534294	Efficacy and safety of BMY 21,502 in Alzheimer disease. Ann Pharmacother. 1996 Dec;30(12):1376-80.

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