Drug General Information
Drug ID	D04UCV
Former ID	DNC004320
Drug Name	8-Chloro-1,2,3,4-tetrahydro-pyrazino[1,2-a]indole
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[526235]
Structure		Download 2D MOL 3D MOL
Formula	C11H11ClN2
Canonical SMILES	C1CN2C(=CC3=C2C=CC(=C3)Cl)CN1
InChI	1S/C11H11ClN2/c12-9-1-2-11-8(5-9)6-10-7-13-3-4-14(10)11/h1-2,5-6,13H,3-4,7H2
InChIKey	QKGDOWUCRMVFPY-UHFFFAOYSA-N
PubChem Compound ID	14595512
Target and Pathway
Target(s)	5-hydroxytryptamine 2A receptor	Target Info	Inhibitor	[526235]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Gap junction
	Serotonergic synapse
	Inflammatory mediator regulation of TRP channels
PANTHER Pathway	5HT2 type receptor mediated signaling pathway
Reactome	Serotonin receptors
	G alpha (q) signalling events
WikiPathways	Serotonin Receptor 2 and STAT3 Signaling
	Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
	SIDS Susceptibility Pathways
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 526235	Bioorg Med Chem Lett. 2002 Jan 21;12(2):155-8.Evaluation of isotryptamine derivatives at 5-HT(2) serotonin receptors.
Ref 526235	Bioorg Med Chem Lett. 2002 Jan 21;12(2):155-8.Evaluation of isotryptamine derivatives at 5-HT(2) serotonin receptors.

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