Drug General Information
Drug ID
D04ULI
Former ID
DIB018379
Drug Name
[3H]PGF2alpha
Synonyms
[3H]dinoprost; [3H]prostaglandin F2alpha
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539254]
Structure
Download
2D MOL
Formula
C20H34O5
InChI
InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1/i4T,7T,12T,15T,16T,17T,18T,19T
InChIKey
PXGPLTODNUVGFL-WEMOGKSOSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Prostaglandin F2-alpha receptor Target Info Agonist [533982]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Reactome Prostanoid ligand receptors
G alpha (q) signalling events
WikiPathways Prostaglandin Synthesis and Regulation
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 539254(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1957).
Ref 533982Cloning and expression of a cDNA for the human prostanoid FP receptor. J Biol Chem. 1994 Jan 28;269(4):2632-6.

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