Drug General Information
Drug ID	D05HFC
Former ID	DNC005092
Drug Name	8-(1,2-Dimethyl-propoxy)-quinolin-2-ylamine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527194]
Structure		Download 2D MOL 3D MOL
Formula	C14H18N2O
Canonical SMILES	CC(C)C(C)OC1=CC=CC2=C1N=C(C=C2)N
InChI	1S/C14H18N2O/c1-9(2)10(3)17-12-6-4-5-11-7-8-13(15)16-14(11)12/h4-10H,1-3H3,(H2,15,16)
InChIKey	UQTSQIVXJFEZMJ-UHFFFAOYSA-N
PubChem Compound ID	10466406
Target and Pathway
Target(s)	Melanin-concentrating hormone receptor 1	Target Info	Inhibitor	[527194]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Peptide ligand-binding receptors
	G alpha (q) signalling events
	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 527194	Bioorg Med Chem Lett. 2004 Oct 4;14(19):4873-7.Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 1.
Ref 527194	Bioorg Med Chem Lett. 2004 Oct 4;14(19):4873-7.Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 1.

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