Drug General Information
Drug ID	D05LXP
Former ID	DNC012319
Drug Name	7,12-Dihydro-7,12-diaza-indeno[1,2-a]fluorene
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[533363]
Structure		Download 2D MOL 3D MOL
Formula	C18H12N2
Canonical SMILES	C1=CC=C2C(=C1)C3=C(N2)C4=C(C=C3)NC5=CC=CC=C54
InChI	1S/C18H12N2/c1-3-7-14-11(5-1)12-9-10-16-17(18(12)20-14)13-6-2-4-8-15(13)19-16/h1-10,19-20H
InChIKey	QQWXDAWSMPLECU-UHFFFAOYSA-N
PubChem Compound ID	4713445
Target and Pathway
Target(s)	Gamma-aminobutyric acid receptor subunit alpha-1	Target Info	Inhibitor	[533363]
	Gamma-aminobutyric acid receptor	Target Info	Inhibitor	[533363]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Retrograde endocannabinoid signaling
	GABAergic synapse
	Morphine addiction
	Nicotine addiction
Reactome	Ligand-gated ion channel transport
	GABA A receptor activation
WikiPathways	SIDS Susceptibility Pathways
	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Iron uptake and transport
References
Ref 533363	J Med Chem. 1988 Sep;31(9):1854-61.Synthesis of novel 3-substituted beta-carbolines as benzodiazepine receptor ligands: probing the benzodiazepine receptor pharmacophore.
Ref 533363	J Med Chem. 1988 Sep;31(9):1854-61.Synthesis of novel 3-substituted beta-carbolines as benzodiazepine receptor ligands: probing the benzodiazepine receptor pharmacophore.

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