Drug Information

Drug General Information
Drug ID
D06KLQ
Former ID
DNC005784
Drug Name
GNF-PF-1550
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527713]
Structure
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2D MOL

3D MOL
Formula
C26H30N4O2
Canonical SMILES
CCN1CCN(CC1)C2=NC3=C(C=C(C=C3)NC(=O)C=CC4=CC=C(C=C4)OC)<br />C(=C2)C
InChI
1S/C26H30N4O2/c1-4-29-13-15-30(16-14-29)25-17-19(2)23-18-21(8-11-24(23)28-25)27-26(31)12-7-20-5-9-22(32-3)10-6-20/h5-12,17-18H,4,13-16H2,1-3H3,(H,27,31)/b12-7+
InChIKey
BYSCWUNLAIWJED-KPKJPENVSA-N
PubChem Compound ID
44403742
Target and Pathway
Target(s) Melanin-concentrating hormone receptor 1 Target Info Inhibitor [527713]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 527713J Med Chem. 2005 Sep 8;48(18):5684-97.6-Acylamino-2-aminoquinolines as potent melanin-concentrating hormone 1 receptor antagonists. Identification, structure-activity relationship, and investigation of binding mode.
Ref 527713J Med Chem. 2005 Sep 8;48(18):5684-97.6-Acylamino-2-aminoquinolines as potent melanin-concentrating hormone 1 receptor antagonists. Identification, structure-activity relationship, and investigation of binding mode.

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