Drug General Information
Drug ID
D06MUZ
Former ID
DIB000113
Drug Name
SDZ-87-469
Drug Type
Small molecular drug
Indication Coronary artery disease [ICD9: 410-414, 429.2; ICD10:I20-I25] Terminated [551702]
Company
Novartis AG
Structure
Download
2D MOL

3D MOL

Formula
C19H22ClNS
Canonical SMILES
c12scc(c1cccc2CN(C/C=C/C#CC(C)(C)C)C)Cl
CAS Number
CAS 87906-31-8
PubChem Compound ID
Target and Pathway
Target(s) Squalene monooxygenase Target Info Modulator [535827]
KEGG Pathway Steroid biosynthesis
Sesquiterpenoid and triterpenoid biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Biosynthesis of antibiotics
PathWhiz Pathway Steroid Biosynthesis
Reactome Cholesterol biosynthesis
Activation of gene expression by SREBF (SREBP)
References
Ref 551702Chemotherapy of fungal diseases. 1990. Page(525-550).
Ref 535827Effects of squalene epoxidase inhibitors on Candida albicans. Antimicrob Agents Chemother. 1992 Aug;36(8):1779-81.

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