Drug Information
Drug General Information | |||||
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Drug ID |
D06XEL
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Former ID |
DCL000106
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Drug Name |
DG051
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Drug Type |
Small molecular drug
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Company |
DeCODE genetics
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Structure |
Download2D MOL |
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Formula |
C21H24ClNO4
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InChI |
InChI=1S/C21H24ClNO4/c22-16-5-7-19(8-6-16)27-20-11-9-18(10-12-20)26-15-17-3-1-13-23(17)14-2-4-21(24)25/h5-12,17H,1-4,13-15H2,(H,24,25)/t17-/m0/s1
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InChIKey |
PVCTYSQBVIGZRU-KRWDZBQOSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Leukotriene A-4 hydrolase | Target Info | Inhibitor | [536080], [536517] | |
BioCyc Pathway | Leukotriene biosynthesis | ||||
KEGG Pathway | Arachidonic acid metabolism | ||||
Metabolic pathways | |||||
PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
WikiPathways | Arachidonic acid metabolism | ||||
Eicosanoid Synthesis | |||||
References | |||||
Ref 541672 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6548). | ||||
Ref 548272 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800024010) | ||||
Ref 536080 | Effects of a 5-lipoxygenase-activating protein inhibitor on biomarkers associated with risk of myocardial infarction: a randomized trial. JAMA. 2005 May 11;293(18):2245-56. | ||||
Ref 536517 | BAY x 1005 attenuates atherosclerosis in apoE/LDLR - double knockout mice. J Physiol Pharmacol. 2007 Sep;58(3):583-8. |
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