Drug Information

Drug General Information
Drug ID
D07AOY
Former ID
DNCL003528
Drug Name
Avarofloxacin
Synonyms
JNJ-Q2
Drug Type
Small molecular drug
Indication Bacterial pneumonia [ICD10:J13, J15] Discontinued in Phase 2 [549103]
Company
Furiex pharmaceuticals
Structure
Download
2D MOL

3D MOL
Formula
C21H23F2N3O4
Canonical SMILES
COC1=C2C(=CC(=C1N3CCCC(=C(CN)F)C3)F)C(=O)C(=CN2C4CC4)C(<br />=O)O
InChI
1S/C21H23F2N3O4/c1-30-20-17-13(19(27)14(21(28)29)10-26(17)12-4-5-12)7-15(22)18(20)25-6-2-3-11(9-25)16(23)8-24/h7,10,12H,2-6,8-9,24H2,1H3,(H,28,29)/b16-11+
InChIKey
VMKVDAAFMQKZJS-LFIBNONCSA-N
PubChem Compound ID
11546234
PubChem Substance ID
16648415, 23668874, 42664244, 74976298, 123086945, 139053591, 162108682, 172232528, 198976524, 228321719, 228321730
Target and Pathway
Target(s) Topoisomerase IV Target Info Modulator [531620]
References
Ref 549103Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800032241)
Ref 531620Antistaphylococcal activities of the new fluoroquinolone JNJ-Q2. Antimicrob Agents Chemother. 2011 Dec;55(12):5512-21.

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