Drug Information

Drug General Information
Drug ID
D07IQS
Former ID
DAP000706
Drug Name
Atazanavir
Synonyms
ATV; ATZ; Atazanavirum; Latazanavir; Reyataz; Zrivada; BMS 232632; CGP 73547; DR7; Atazanavir (INN); Atazanavir [INN:BAN];BMS-232632; CGP-73547; Reyataz (TN); Reyataz, BMS-232632, Atazanavir; Reyataz(TM) (*1:1 sulfate*); Dimethyl (3S,8S,9S,12S)-9-benzyl-3,12-di-tert-butyl-8-hydroxy-4,11-dioxo-6-[4-(2-pyridyl)benzyl]-2,5,6,10,13-pentaazatetradecanedioate; METHYL [(1S,4S,5S,10S)-4-BENZYL-1,10-DI-TERT-BUTYL-5-HYDROXY-2,9,12-TRIOXO-7-(4-PYRIDIN-2-YLBENZYL)-13-OXA-3,7,8,11-TETRAAZATETRADEC-1-YL]CARBAMATE; Methyl N-[(2S)-1-[2-[(2S,3S)-2-hydroxy-3-[[(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoyl]amino]-4-phenylbutyl]-2-[(4-pyridin-2-ylphenyl)methyl]hydrazinyl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate; (2S)-N-(3-{[(2S)-2-(Methoxycarbonylamino)-3,3-dimethylbutanoylamino][(4-(2-pyridyl)phenyl)methyl]amino}(1S,2S)-2-hydroxy-1-benzylpropyl)-2-(methoxycarbonylamino)-3,3-dimethylbutanamide; (3S,8S,9S,12S)-3,12-BIS(1,1-DIMETHYLETHYL)-8-HYDROXY-4,11-DIOXO-9-(PHENYLMETHYL)-6-[[4-(2-PYRIDINYL)PHENYL]METHYL]-2,5,6,10,13-PENTAAZATETRADECANEDIOIC ACID DIMETHYL ESTER
Drug Type
Small molecular drug
Indication Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] Approved [536361]
Therapeutic Class
Anti-HIV Agents
Company
Bristol-Myers Squibb
Structure
Download
2D MOL

3D MOL
Formula
C38H52N6O7
Canonical SMILES
CC(C)(C)C(C(=O)NC(CC1=CC=CC=C1)C(CN(CC2=CC=C(C=C2)C3=CC<br />=CC=N3)NC(=O)C(C(C)(C)C)NC(=O)OC)O)NC(=O)OC
InChI
1S/C38H52N6O7/c1-37(2,3)31(41-35(48)50-7)33(46)40-29(22-25-14-10-9-11-15-25)30(45)24-44(43-34(47)32(38(4,5)6)42-36(49)51-8)23-26-17-19-27(20-18-26)28-16-12-13-21-39-28/h9-21,29-32,45H,22-24H2,1-8H3,(H,40,46)(H,41,48)(H,42,49)(H,43,47)/t29-,30-,31+,32+/m0/s1
InChIKey
AXRYRYVKAWYZBR-GASGPIRDSA-N
CAS Number
CAS 198904-31-3
PubChem Compound ID
148192
PubChem Substance ID
621982, 10249838, 14715932, 14766361, 14790731, 15047322, 17436380, 24276961, 46225140, 46393831, 46508504, 46512956, 49831615, 50067727, 50070909, 50780515, 51091799, 53801241, 57346722, 85177037, 85177040, 85177051, 85177056, 87225781, 92308998, 92729699, 99437162, 103338831, 104418454, 124757264, 124894049, 125164068, 125267482, 126649083, 126665840, 126731250, 127338999, 127339000, 127474087, 134337995, 134339780, 135105507, 135692446, 137004575, 142410398, 143496681, 144206632, 152234924, 152344127, 160647610
ChEBI ID
ChEBI:37924
SuperDrug ATC ID
J05AE08
Target and Pathway
Target(s) HIV protease Target Info Modulator [556264]
References
Ref 536361Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20.
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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