Drug Information

Drug General Information
Drug ID
D07MPJ
Former ID
DIB003903
Drug Name
A-75925
Synonyms
A-74704; A-75925; A-76928; A-77003; Protease inhibitors, Abbott
Drug Type
Small molecular drug
Indication Viral infections [ICD9: 054.0, 054.1, 054.2, 054.3, 075, 771.2, 052, 053; ICD10:B01, B02, A60, B00, B27, G05.1, P35.2] Discontinued in Phase 2 [545458]
Company
Abbott Laboratories
Structure
Download
2D MOL

3D MOL
Formula
C44H54N4O8
Canonical SMILES
C(=O)(N[C@H](C(=O)N[C@H]([C@@H]([C@@H]([C@@H](NC(=O)[C@<br />@H](NC(=O)N(Cc1ncccc1)C)C(C)C)Cc1ccccc1)O)O)Cc1ccccc1)C<br />(C)C)N(Cc1ncccc1)C
PubChem Compound ID
72290
Target and Pathway
Target(s) HIV protease Target Info Inhibitor [534596]
References
Ref 545458Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003337)
Ref 534596Solvation studies of DMP323 and A76928 bound to HIV protease: analysis of water sites using grand canonical Monte Carlo simulations. Protein Sci. 1998 Mar;7(3):573-9.

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