Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D07SRX
|
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| Former ID |
DIB021154
|
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| Drug Name |
AG-E-85378
|
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| Synonyms |
AG-E-85378
|
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| Drug Type |
Small molecular drug
|
||||
| Indication | Discovery agent | Investigative | [529047] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C19H16ClN3O
|
||||
| InChI |
InChI=1S/C19H16ClN3O/c20-15-5-7-16(8-6-15)23-19(24)17-3-1-2-4-18(17)22-13-14-9-11-21-12-10-14/h1-12,22H,13H2,(H,23,24)
|
||||
| InChIKey |
GGPZCOONYBPZEW-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | Inhibitor | [529047] | |
| NetPath Pathway | IL2 Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathway | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY network | |||||
| References | |||||
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