Drug Information

Drug General Information
Drug ID
D08DAE
Former ID
DNC011828
Drug Name
CHOLINE
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467788]
Structure
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2D MOL

3D MOL
Formula
C5H14NO+
InChI
InChI=1S/C5H14NO/c1-6(2,3)4-5-7/h7H,4-5H2,1-3H3/q+1
InChIKey
OEYIOHPDSNJKLS-UHFFFAOYSA-N
CAS Number
CAS 62-49-7
PubChem Compound ID
305
PubChem Substance ID
2233, 3414, 539149, 590083, 608363, 821095, 821590, 821695, 828440, 829111, 841597, 6152900, 7767976, 7886600, 7978932, 8143147, 8150565, 11110922, 11335282, 11360521, 11363152, 11365714, 11368276, 11374671, 11376438, 11461493, 11485711, 11489754, 11492682, 11494072, 12125265, 14710526, 17435852, 24438681, 24892739, 32656435, 39988658, 46392765, 46508132, 47365030, 47440099, 47736312, 48409865, 49754889, 49754890, 49903094, 50110963, 51073513, 53776826, 53788168
Target and Pathway
Target(s) Neuronal acetylcholinereceptor subunit alpha-2 Target Info Inhibitor [527014]
KEGG Pathway Neuroactive ligand-receptor interaction
PANTHER Pathway Nicotinic acetylcholine receptor signaling pathway
Reactome Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
Highly calcium permeable nicotinic acetylcholine receptors
WikiPathways Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
References
Ref 467788(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4551).
Ref 527014Bioorg Med Chem Lett. 2004 Apr 19;14(8):1845-8.Pharmacology of the agonist binding sites of rat neuronal nicotinic receptor subtypes expressed in HEK 293 cells.

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