Drug Information

Drug General Information
Drug ID
D08XFR
Former ID
DIB010895
Drug Name
AEZS-115
Synonyms
D-85108; LHRH antagonist, Solvay; LHRH antagonist, Zentaris; ZEN-019; LHRH antagonists, Solvay/AEterna Zentaris
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Investigative [543648]
Company
AEterna Zentaris Inc
Target and Pathway
Target(s) Gonadotropin-releasing hormone receptor Target Info Antagonist [543648]
KEGG Pathway Neuroactive ligand-receptor interaction
GnRH signaling pathway
NetPath Pathway IL1 Signaling Pathway
IL2 Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome Hormone ligand-binding receptors
G alpha (q) signalling events
WikiPathways Gastrin-CREB signalling pathway via PKC and MAPK
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 543648(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 256).
Ref 543648(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 256).

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