TTD | Drug: D09DSK

Drug General Information
Drug ID	D09DSK
Former ID	DIB011206
Drug Name	JWH-051
Synonyms	CB2 receptor agonists (pain); CB2 receptor agonists (pain), Merck
Indication	Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89]		Investigative	[543878]
Company	Merck & Co Inc
Structure		Download 2D MOL 3D MOL
Canonical SMILES	c1([C@@]2(O)[C@@H]3CCCC[C@@H]3N(CC2)C(=O)c2cnc(cc2)C)cc<br />ccc1
Target and Pathway
Target(s)	Cannabinoid receptor 2	Target Info	Agonist	[543878]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Class A/1 (Rhodopsin-like receptors)
Reactome	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Small Ligand GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 543878	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 57).
Ref 543878	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 57).

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Drug Information