Drug General Information
Drug ID	D09GQI
Former ID	DNC011536
Drug Name	2-(1H-Imidazol-4-yl)-cyclopropylamine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[526614]
Structure		Download 2D MOL 3D MOL
Formula	C6H9N3
Canonical SMILES	C1C(C1N)C2=CN=CN2
InChI	1S/C6H9N3/c7-5-1-4(5)6-2-8-3-9-6/h2-5H,1,7H2,(H,8,9)/t4-,5+/m1/s1
InChIKey	OWWNABDDYQLERE-UHNVWZDZSA-N
PubChem Compound ID	10986211
Target and Pathway
Target(s)	Histamine H3 receptor	Target Info	Inhibitor	[526614]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Histamine receptors
	G alpha (i) signalling events
WikiPathways	Monoamine Transport
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 526614	J Med Chem. 2003 May 8;46(10):1980-8.Cyclopropane-based conformational restriction of histamine. (1S,2S)-2-(2-aminoethyl)-1-(1H-imidazol-4-yl)cyclopropane, a highly selective agonist for the histamine H3 receptor, having a cis-cyclopropane structure.
Ref 526614	J Med Chem. 2003 May 8;46(10):1980-8.Cyclopropane-based conformational restriction of histamine. (1S,2S)-2-(2-aminoethyl)-1-(1H-imidazol-4-yl)cyclopropane, a highly selective agonist for the histamine H3 receptor, having a cis-cyclopropane structure.

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