Drug Information

Drug General Information
Drug ID
D09KDS
Former ID
DNC007936
Drug Name
Adamantan-1-yl-(4-ethyl-piperazin-1-yl)-methanone
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528722]
Structure
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2D MOL

3D MOL
Formula
C17H28N2O
Canonical SMILES
CCN1CCN(CC1)C(=O)C23CC4CC(C2)CC(C4)C3
InChI
1S/C17H28N2O/c1-2-18-3-5-19(6-4-18)16(20)17-10-13-7-14(11-17)9-15(8-13)12-17/h13-15H,2-12H2,1H3
InChIKey
XOWWNQSYPPTVEH-UHFFFAOYSA-N
PubChem Compound ID
4348598
Target and Pathway
Target(s) Corticosteroid 11-beta-dehydrogenase, isozyme 1 Target Info Inhibitor [528722]
KEGG Pathway Steroid hormone biosynthesis
Metabolism of xenobiotics by cytochrome P450
Metabolic pathways
Chemical carcinogenesis
NetPath Pathway IL1 Signaling Pathway
FSH Signaling Pathway
PathWhiz Pathway Steroidogenesis
Reactome Glucocorticoid biosynthesis
WikiPathways Prostaglandin Synthesis and Regulation
Metabolism of steroid hormones and vitamin D
Glucocorticoid & Mineralcorticoid Metabolism
References
Ref 528722Bioorg Med Chem Lett. 2007 May 15;17(10):2838-43. Epub 2007 Feb 25.Discovery and biological evaluation of adamantyl amide 11beta-HSD1 inhibitors.
Ref 528722Bioorg Med Chem Lett. 2007 May 15;17(10):2838-43. Epub 2007 Feb 25.Discovery and biological evaluation of adamantyl amide 11beta-HSD1 inhibitors.

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