Drug Information
Drug General Information | |||||
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Drug ID |
D09QDP
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Former ID |
DAP001361
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Drug Name |
Clorgyline
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Synonyms |
Chlorgyline; Clorgilin; Clorgilina; Clorgiline; Clorgilinum; Clorgiline [INN]; M and B 9302; Clorgilina [INN-Spanish]; Clorgiline (INN); Clorgilinum [INN-Latin]; M & B 9302; N-methyl-n-propargyl-3-(2,4-dichlorophenoxy)propylamine; N-(3-(2,4-Dichlorophenoxy)propyl)-N-methyl-2-propynylamine; N-[3-(2,4-DICHLOROPHENOXY)PROPYL]-N-METHYL-N-PROP-2-YNYLAMINE; 2-Propyn-1-amine, N-(3-(2,4-dichlorophenoxy)propyl)-N-methyl-(9CI); 3-(2,4-dichlorophenoxy)-N-methyl-N-prop-2-ynylpropan-1-amine
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Drug Type |
Small molecular drug
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Therapeutic Class |
Antiparkinson Agents
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Structure |
Download2D MOL |
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Formula |
C13H15Cl2NO
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InChI |
InChI=1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3
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InChIKey |
BTFHLQRNAMSNLC-UHFFFAOYSA-N
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CAS Number |
CAS 17780-72-2
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PubChem Compound ID | |||||
PubChem Substance ID |
13850, 3249453, 5551145, 7888938, 8152714, 11111452, 11111453, 11466372, 11467492, 11486064, 15197430, 17397401, 29223477, 46507410, 46515873, 47216895, 47736618, 47959893, 48259379, 48334629, 49698444, 50026762, 50111129, 53787182, 57322251, 57389000, 74906189, 85209991, 85787507, 89449655, 90341614, 103167716, 104306235, 121598837, 124749963, 124880698, 126407870, 127564762, 134338573, 134993341, 137237445, 137725548, 160967085, 163425653, 163667991, 178103249, 179148711, 196408559, 198975950, 226443490
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Target and Pathway | |||||
Target(s) | Amine oxidase [flavin-containing] A | Target Info | Inhibitor | [537290] | |
KEGG Pathway | Glycine, serine and threonine metabolism | ||||
Arginine and proline metabolism | |||||
Histidine metabolism | |||||
Tyrosine metabolism | |||||
Phenylalanine metabolism | |||||
Tryptophan metabolism | |||||
Drug metabolism - cytochrome P450 | |||||
Metabolic pathways | |||||
Serotonergic synapse | |||||
Dopaminergic synapse | |||||
Cocaine addiction | |||||
Amphetamine addiction | |||||
Alcoholism | |||||
NetPath Pathway | IL4 Signaling Pathway | ||||
References | |||||
Ref 537290 | Further investigation into the mechanism of tachykinin NK(2) receptor-triggered serotonin release from guinea-pig proximal colon. J Pharmacol Sci. 2009 May;110(1):122-6. Epub 2009 May 8. | ||||
Ref 541746 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6636). | ||||
Ref 551871 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 |
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