TTD | Drug: D09TWW

Drug General Information
Drug ID	D09TWW
Former ID	DIB019819
Drug Name	EP 171
Synonyms	EP-171; EP171
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539268]
Structure		Download 2D MOL
Formula	C23H29FO5
InChI	InChI=1S/C23H29FO5/c24-16-7-10-18(11-8-16)28-15-17(25)9-12-20-19(21-13-14-22(20)29-21)5-3-1-2-4-6-23(26)27/h1,3,7-12,17,19-22,25H,2,4-6,13-15H2,(H,26,27)/b3-1-,12-9+/t17-,19+,20+,21-,22+/m0/s1
InChIKey	JEUSDRLWFSRHSX-XUEDOEMRSA-N
PubChem Compound ID	5311384
PubChem Substance ID	7980453, 39341064, 57359460, 75241620, 114155956, 135650233
Target and Pathway
Target(s)	Thromboxane A2 receptor	Target Info	Agonist	[533341]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Platelet activation
Reactome	Prostanoid ligand receptors
	G alpha (q) signalling events
	G alpha (12/13) signalling events
	Thromboxane signalling through TP receptor
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Small Ligand GPCRs
	Signal amplification
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 539268	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1971).
Ref 533341	EP 171: a high affinity thromboxane A2-mimetic, the actions of which are slowly reversed by receptor blockade. Br J Pharmacol. 1989 Apr;96(4):875-87.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.

Drug Information