Drug Information

Drug General Information
Drug ID
D09XOF
Former ID
DIB001002
Drug Name
NY-ESO-1 vaccine
Synonyms
Cancer vaccine (peptides), Ludwig Institute; NY-ESO-1b; NY-ESO-1 OLP-4; NY-ESO-1 peptide immunotherapy, Ludwig Institute; NY-ESO-1 vaccine (peptides); NY-ESO-1 DP4 peptide (157-170); NY-ESO-1 vaccine (peptides), Ludwig Institute
Drug Type
Vaccine
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Phase 1 [521703]
Company
Ludwig Institute for Cancer Research
Structure
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2D MOL

3D MOL
Canonical SMILES
N([C@H](C(=O)N)CS)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]<br />(NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC<br />(=O)[C@@H](N)CO)CC(C)C)CC(C)C)CCSC)Cc1c[nH]c2c1cccc2)[C<br />@@H](C)CC)[C@H](O)C)CCC(=O)N
Target and Pathway
Target(s) NY-ESO-1 Target Info [544008]
References
Ref 521703ClinicalTrials.gov (NCT00199836) A Pilot Study of NY-ESO-1b Peptide Plus CpG 7909 and Montanide ISA-51 in Patients With Cancer.. U.S. National Institutes of Health.
Ref 544008Multiepitope CD8+ T cell response to a NY-ESO-1 peptide vaccine results in imprecise tumor targeting. J Clin Invest. 2002 December 15; 110(12): 1813-1822.

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