Drug Information

Drug General Information
Drug ID
D0A1VL
Former ID
DPR000015
Drug Name
AR-R-1589
Indication Obesity; Eating disorders [ICD9: 278, 307.5; ICD10:E66, F50] Preclinical [536122]
Company
Fisons; AstraZeneca
Target and Pathway
Target(s) Cholecystokinin receptor type A Target Info Agonist [536122]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Insulin secretion
Pancreatic secretion
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 536122Emerging drugs for obesity: linking novel biological mechanisms to pharmaceutical pipelines. Expert Opin Emerg Drugs. 2005 Aug;10(3):643-60.
Ref 536122Emerging drugs for obesity: linking novel biological mechanisms to pharmaceutical pipelines. Expert Opin Emerg Drugs. 2005 Aug;10(3):643-60.

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