Drug Information

Drug General Information
Drug ID
D0AR7L
Former ID
DIB005323
Drug Name
SAR-389644
Synonyms
SAR-389644C; Prostaglandin D2 antagonist (asthma/allergic rhinitis), sanofi-aventis
Indication Allergic rhinitis [ICD9: 472.0, 477, 995.3; ICD10:J00, J30, J31.0, T78.4] Phase 1 [548481]
Company
Sanofi
Target and Pathway
Target(s) Prostaglandin D2 receptor Target Info Antagonist [550898]
KEGG Pathway Neuroactive ligand-receptor interaction
Pathway Interaction Database Thromboxane A2 receptor signaling
PathWhiz Pathway Intracellular Signalling Through PGD2 receptor and Prostaglandin D2
Reactome Prostanoid ligand receptors
G alpha (s) signalling events
WikiPathways Prostaglandin Synthesis and Regulation
GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 548481Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025865)
Ref 550898US patent application no. 2008,0300,217, Combination therapy with fumaric acid esters for the treatment of autoimmune and,or inflammatory disorders.

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