Drug Information
Drug General Information | |||||
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Drug ID |
D0C0KJ
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Former ID |
DIB020247
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Drug Name |
LTE4
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Synonyms |
leukotriene E; leukotriene E4
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [540309] | ||
Structure |
Download2D MOL |
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Formula |
C23H37NO5S
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InChI |
InChI=1S/C23H37NO5S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-21(30-18-19(24)23(28)29)20(25)15-14-17-22(26)27/h6-7,9-13,16,19-21,25H,2-5,8,14-15,17-18,24H2,1H3,(H,26,27)(H,28,29)/b7-6-,10-9-,12-11+,16-13+/t19-,20-,21+/m0/s1
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InChIKey |
OTZRAYGBFWZKMX-FRFVZSDQSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
8236, 4266070, 7979753, 8143276, 8616419, 16344702, 26756770, 39289868, 48409442, 50111414, 57357904, 74701367, 96099805, 103591347, 104138918, 113854149, 127316814, 127316815, 127316816, 127316817, 127316818, 135651514, 137006567, 138355247, 164228112, 164761568, 178102487, 179293257, 198951720, 198991667, 236466655, 250135039, 252455510, 252467954
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Target and Pathway | |||||
Target(s) | GPR17 | Target Info | Agonist | [529783] | |
Cysteinyl leukotriene receptor 1 | Target Info | Agonist | [525529] | ||
Leukotriene CysLT2 receptor | Target Info | Agonist | [531263] | ||
Pathway Interaction Database | Endothelinsendothelinpathway:Endothelins | ||||
References | |||||
Ref 525529 | Characterization of the human cysteinyl leukotriene CysLT1 receptor. Nature. 1999 Jun 24;399(6738):789-93. | ||||
Ref 529783 | The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair. PLoS One. 2008;3(10):e3579. | ||||
Ref 531263 | Differential signaling of cysteinyl leukotrienes and a novel cysteinyl leukotriene receptor 2 (CysLT?? agonist, N-methyl-leukotriene C?? in calcium reporter and beta arrestin assays. Mol Pharmacol. 2011 Feb;79(2):270-8. |
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