TTD | Drug: D0C5RQ

Drug General Information
Drug ID	D0C5RQ
Former ID	DIB020919
Drug Name	SB-568849
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[538803]
Structure		Download 2D MOL 3D MOL
Formula	C26H27F3N2O3
InChI	InChI=1S/C26H27F3N2O3/c1-4-30-15-16-34-23-14-13-22(17-24(23)33-3)31(2)25(32)20-7-5-18(6-8-20)19-9-11-21(12-10-19)26(27,28)29/h5-14,17,30H,4,15-16H2,1-3H3
InChIKey	SCEZYQWIHJHQDL-UHFFFAOYSA-N
PubChem Compound ID	16046160
PubChem Substance ID	41805283, 135651010
Target and Pathway
Target(s)	Melanin-concentrating hormone receptor 1	Target Info	Antagonist	[528310]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Peptide ligand-binding receptors
	G alpha (q) signalling events
	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 538803	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1312).
Ref 528310	Discovery of potent and stable conformationally constrained analogues of the MCH R1 antagonist SB-568849. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4872-8. Epub 2006 Jul 12.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.

Drug Information