TTD | Drug: D0EH5Z

Drug General Information
Drug ID	D0EH5Z
Former ID	DNC013656
Drug Name	2-(3,5-dimethoxy-4-phenethoxyphenyl)ethanamine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529336]
Structure		Download 2D MOL 3D MOL
Formula	C18H23NO3
Canonical SMILES	COC1=CC(=CC(=C1OCCC2=CC=CC=C2)OC)CCN
InChI	1S/C18H23NO3/c1-20-16-12-15(8-10-19)13-17(21-2)18(16)22-11-9-14-6-4-3-5-7-14/h3-7,12-13H,8-11,19H2,1-2H3
InChIKey	FKXBCTFKCKEDNI-UHFFFAOYSA-N
PubChem Compound ID	44567543
Target and Pathway
Target(s)	5-hydroxytryptamine 2A receptor	Target Info	Inhibitor	[529336]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Gap junction
	Serotonergic synapse
	Inflammatory mediator regulation of TRP channels
PANTHER Pathway	5HT2 type receptor mediated signaling pathway
Reactome	Serotonin receptors
Reactome	G alpha (q) signalling events
WikiPathways	Serotonin Receptor 2 and STAT3 Signaling
	Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
	SIDS Susceptibility Pathways
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 529336	Bioorg Med Chem. 2008 Apr 15;16(8):4661-9. Epub 2008 Feb 14.The role of lipophilicity in determining binding affinity and functional activity for 5-HT2A receptor ligands.
Ref 529336	Bioorg Med Chem. 2008 Apr 15;16(8):4661-9. Epub 2008 Feb 14.The role of lipophilicity in determining binding affinity and functional activity for 5-HT2A receptor ligands.

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Drug Information