Drug Information

Drug General Information
Drug ID
D0F0OK
Former ID
DAP001199
Drug Name
Sulfametopyrazine
Synonyms
Dalysep; Kelfizin; Kelfizina; Kelfizine; Longum; Polycidal; SMP; SULFALENE; Solfametopirazina; Sulfalen; Sulfaleno; Sulfalenum; Sulfamethopyrazine; Sulfamethoxypyrazine; Sulfamethoxysuccinate; Sulfametoxypyridazin; Sulfapyrazinemethoxine; Sulfapyrazinemethoxyine; Sulfapyrazinemethoxyne; Sulfapyrazinmethoxine; Sulphalene; Sulphametopyrazine; Kelfizine W; Solfametopirazina [DCIT]; AS 18908; CBMicro_013257; FI 5978; WR 4629; Farmitalia 204/122; Kelfizina (TN); Sulfalene (USAN); Sulfalene [USAN:INN]; Sulfaleno [INN-Spanish]; Sulfalenum [INN-Latin]; Sulfamethopyrazine (JAN); N1-(3-Methoxypyrazinyl)sulfanilamide; N(sup 1)-(3-Methoxypyrazinyl)sulfanilamide; N(sup1)-(3-Methoxypyrazinyl)sulfanilamide; N(sup 1)-(3-Methoxy-2-pyrazinyl)sulfanilamide; N(sup1)-(3-Methoxy-2-pyrazinyl)sulfanilamide; Sulfanilamide, N1-(3-methoxypyrazinyl)-(8CI); 2-(p-Aminobenzenesulfanamide)-3-methoxypyrazine; 2-(p-Aminobenzenesulfonamido)-3-methoxypyrazine; 2-Methoxy-3-sulfanilamidopyrazine; 2-Sulfanilamide 3-methoxy-pyrazine; 2-Sulfanilamido-3-methoxypyrazine; 3-Methoxy-2-sulfanilamidopyrazine; 3-Methoxy-2-sulfapyrazine; 3-Methoxypyrazine sulfanilamide; 4-Amino-N-(3-methoxy-pyrazin-2-yl)-benzenesulfonamide; 4-Amino-N-(3-methoxypyrazinyl)-benzenesulfonamide; 4-Amino-N-(3-methoxypyrazinyl)benzenesulfonamide; 4-amino-N-(3-methoxypyrazin-2-yl)benzenesulfonamide
Drug Type
Small molecular drug
Indication Urinary tract infections [ICD9: 599; ICD10:N39.0] Withdrawn from market [550724]
Therapeutic Class
Antiinfective Agents
Structure
Download
2D MOL

3D MOL
Formula
C11H12N4O3S
Canonical SMILES
COC1=NC=CN=C1NS(=O)(=O)C2=CC=C(C=C2)N
InChI
1S/C11H12N4O3S/c1-18-11-10(13-6-7-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,15)
InChIKey
KXRZBTAEDBELFD-UHFFFAOYSA-N
CAS Number
CAS 152-47-6
PubChem Compound ID
9047
PubChem Substance ID
409142, 583006, 604395, 7548079, 7848279, 8062608, 8156436, 11160573, 14799628, 17437592, 29216164, 29227665, 46505111, 47365723, 50048736, 50086577, 57325395, 58023655, 78686684, 81066133, 81093065, 92711298, 93373982, 104319411, 105085796, 124666553, 124766274, 124966247, 125170101, 125341730, 126603293, 126631009, 126657443, 126670666, 128449820, 131300043, 134338439, 134973755, 137003197, 143449411, 144052070, 144205397, 160964009, 162183044, 162211701, 163123923, 163412175, 163601400, 170031297, 170465930
SuperDrug ATC ID
J01ED02
SuperDrug CAS ID
cas=000152476
Target and Pathway
Target(s) Dihydropteroate synthetase Target Info Inhibitor [535512]
References
Ref 550724Drug information of Sulfametopyrazine, 2008. eduDrugs.
Ref 535512Plasmodium falciparum dihydrofolate reductase Val-16 and Thr-108 mutation associated with in vivo resistance to antifolate drug: a case study. Indian J Malariol. 2001 Sep-Dec;38(3-4):76-83.

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