Drug Information

Drug General Information
Drug ID
D0F1CP
Drug Name
EPLIVANSERIN MESILATE
Synonyms
1(Z)-[2-(Dimethylamino)ethoxyimino]-1-(2-fluorophenyl)-3-(4-hydroxyphenyl)-2(E)-propene methanesulfonate; EPLIVANSERIN MESILATE; Eplivanserin mesilate < Prop INNM >; SR-46349C
Indication Unspecified Investigative [1560503]
Target and Pathway
Target(s) 5-hydroxytryptamine 2A receptor Target Info Modulator
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Serotonergic synapse
Inflammatory mediator regulation of TRP channels
PANTHER Pathway 5HT2 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (q) signalling events
WikiPathways Serotonin Receptor 2 and STAT3 Signaling
Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
SIDS Susceptibility Pathways
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 1560503Role of 5-HT2A receptor antagonists in the treatment of insomnia

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