Drug General Information
Drug ID
D0F1EX
Former ID
DAP000415
Drug Name
Alclometasone
Synonyms
Aclometasone; Aclovate (TN); Alclometasone (INN); Alclometasone [INN:BAN]; (7R,8S,9S,10R,11S,13S,14S,16R,17R)-7-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one; (7alpha,11beta,16alpha)-7-chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione; 7alpha-Chloro-16alpha-methylprednisolone
Drug Type
Small molecular drug
Indication Inflammatory disease [ICD9: 140-229, 147, 173, 573.3, 710-719; ICD10:C11, C44, K75.9, M00-M25] Approved [536361]
Therapeutic Class
Antiinflammatory Agents
Company
GlaxoSmithKline
Structure
Download
2D MOL

3D MOL

Formula
C22H29ClO5
Canonical SMILES
CC1CC2C3C(CC4=CC(=O)C=CC4(C3C(CC2(C1(C(=O)CO)O)C)O)C)Cl
InChI
1S/C22H29ClO5/c1-11-6-14-18-15(23)8-12-7-13(25)4-5-20(12,2)19(18)16(26)9-21(14,3)22(11,28)17(27)10-24/h4-5,7,11,14-16,18-19,24,26,28H,6,8-10H2,1-3H3/t11-,14+,15-,16+,18-,19+,20+,21+,22+/m1/s1
InChIKey
FJXOGVLKCZQRDN-PHCHRAKRSA-N
CAS Number
CAS 66734-13-2
PubChem Compound ID
PubChem Substance ID
SuperDrug ATC ID
D07AB10; S01BA10
SuperDrug CAS ID
cas=066734132
Target and Pathway
Target(s) Corticosteroid-binding globulin Target Info Binder [537683]
References
Ref 536361Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20.
Ref 537683The anti-inflammatory effects of LY178002 and LY256548. Agents Actions. 1989 Jun;27(3-4):300-2.

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