Drug Information
Drug General Information | |||||
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Drug ID |
D0F6XR
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Former ID |
DNC000583
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Drug Name |
DV-7028
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Drug Type |
Small molecular drug
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Indication | Cardiovascular disorder [ICD10:I00-I99] | Terminated | [545055] | ||
Structure |
Download2D MOL |
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Formula |
C25H29FN4O7
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Canonical SMILES |
C1CCN2C(=NC(=O)N(C2=O)CCN3CCC(CC3)C(=O)C4=CC=C(C=C4)F)C<br />1.C(=CC(=O)O)C(=O)O
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InChI |
1S/C21H25FN4O3.C4H4O4/c22-17-6-4-15(5-7-17)19(27)16-8-11-24(12-9-16)13-14-26-20(28)23-18-3-1-2-10-25(18)21(26)29;5-3(6)1-2-4(7)8/h4-7,16H,1-3,8-14H2;1-2H,(H,5,6)(H,7,8)/b;2-1-
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InChIKey |
GVSYIVYQDRVBAL-BTJKTKAUSA-N
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CAS Number |
CAS 133364-63-3
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | 5-hydroxytryptamine 2A receptor | Target Info | Agonist | [537955], [538116], [538117] | |
PANTHER Pathway | 5HT2 type receptor mediated signaling pathway | ||||
References | |||||
Ref 537955 | Evidence that 5-HT2A receptors are not involved in 5-HT-mediated thermoregulation in mice. Pharmacol Biochem Behav. 1995 Dec;52(4):755-8. | ||||
Ref 538116 | A potent 5-hydroxytryptamine receptor (5-HT2A) antagonist, DV-7028, delays arterial thrombosis development in rats. Thromb Res. 1998 Jun 15;90(6):259-70. | ||||
Ref 538117 | Vascular and cardiac effects of DV-7028, a selective, 5-HT2-receptor antagonist in rats. J Cardiovasc Pharmacol. 1998 Aug;32(2):266-73. |
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