Drug Information

Drug General Information
Drug ID
D0G0CJ
Former ID
DNC010478
Drug Name
2-(N-Cyclopentylamino)-3'-bromopropiophenone
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530728]
Structure
Download
2D MOL

3D MOL
Formula
C14H18BrNO
Canonical SMILES
CC(C(=O)C1=CC(=CC=C1)Br)NC2CCCC2
InChI
1S/C14H18BrNO/c1-10(16-13-7-2-3-8-13)14(17)11-5-4-6-12(15)9-11/h4-6,9-10,13,16H,2-3,7-8H2,1H3
InChIKey
ZZWUEOYQVWAKCJ-UHFFFAOYSA-N
PubChem Compound ID
45141380
Target and Pathway
Target(s) Sodium-dependent dopamine transporter Target Info Inhibitor [530728]
Sodium-dependent noradrenaline transporter Target Info Inhibitor [530728]
KEGG Pathway Dopaminergic synapse
Parkinson's disease
Cocaine addiction
Amphetamine addiction
Alcoholism
PANTHER Pathway Adrenaline and noradrenaline biosynthesis
Parkinson disease
Dopamine receptor mediated signaling pathwayP00001:Adrenaline and noradrenaline biosynthesis
Pathway Interaction Database Alpha-synuclein signaling
Reactome Na+/Cl- dependent neurotransmitter transportersR-HSA-442660:Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Dopaminergic Neurogenesis
Parkinsons Disease Pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
Neurotransmitter Clearance In The Synaptic CleftWP727:Monoamine Transport
References
Ref 530728J Med Chem. 2010 Mar 11;53(5):2204-14.Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for smoking cessation.
Ref 530728J Med Chem. 2010 Mar 11;53(5):2204-14.Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for smoking cessation.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.