TTD | Drug: D0G3RN

Drug General Information
Drug ID	D0G3RN
Former ID	DNC008439
Drug Name	VUF-10214
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529387]
Structure		Download 2D MOL 3D MOL
Formula	C13H14Cl2N4O
Canonical SMILES	CN1CCN(CC1)C2=NC3=CC(=C(C=C3NC2=O)Cl)Cl
InChI	1S/C13H14Cl2N4O/c1-18-2-4-19(5-3-18)12-13(20)17-11-7-9(15)8(14)6-10(11)16-12/h6-7H,2-5H2,1H3,(H,17,20)
InChIKey	MFJVHWQDKIEBCM-UHFFFAOYSA-N
PubChem Compound ID	11301441
Target and Pathway
Target(s)	Histamine H3 receptor	Target Info	Inhibitor	[529387]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Histamine receptors
Reactome	G alpha (i) signalling events
WikiPathways	Monoamine Transport
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 529387	J Med Chem. 2008 Apr 24;51(8):2457-67. Epub 2008 Mar 22.Fragment based design of new H4 receptor-ligands with anti-inflammatory properties in vivo.
Ref 529387	J Med Chem. 2008 Apr 24;51(8):2457-67. Epub 2008 Mar 22.Fragment based design of new H4 receptor-ligands with anti-inflammatory properties in vivo.

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Drug Information