Drug Information
Drug General Information | |||||
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Drug ID |
D0H0EM
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Former ID |
DIB016839
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Drug Name |
Dofequidar fumarate
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Synonyms |
MS-209; Dofequidar fumarate < Prop INNM >; 1-(Diphenylacetyl)-4-[(2RS)-2-hydroxy-3-(5-quinolyloxy)propyl]piperazine sesquifumarate; 1-[4-(2,2-Diphenylacetyl)piperazin-1-yl]-3-(quinoliln-5-yloxy)-2-propanol sesquifumarate; 5-[3-[4-(2,2-Diphenylacetyl)piperazin-1-yl]-2-hydroxypropoxy]quinoline sesquifumarate
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Drug Type |
Small molecular drug
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Indication | Cancer [ICD9: 140-229; ICD10:C00-C96] | Discontinued in Phase 3 | [533758] | ||
Structure |
Download2D MOL |
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Formula |
C30H31N3O3
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Canonical SMILES |
C1CN(CCN1CC(COC2=CC=CC3=C2C=CC=N3)O)C(=O)C(C4=CC=CC=C4)<br />C5=CC=CC=C5
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InChI |
1S/C30H31N3O3/c34-25(22-36-28-15-7-14-27-26(28)13-8-16-31-27)21-32-17-19-33(20-18-32)30(35)29(23-9-3-1-4-10-23)24-11-5-2-6-12-24/h1-16,25,29,34H,17-22H2
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InChIKey |
KLWUUPVJTLHYIM-UHFFFAOYSA-N
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CAS Number |
CAS 129716-58-1
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Multidrug resistance protein 3 | Target Info | Modulator | [533758] | |
KEGG Pathway | ABC transporters | ||||
Bile secretion | |||||
References |
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