Drug General Information
Drug ID	D0H5LC
Former ID	DIB008711
Drug Name	CHPMPC
Synonyms	Cyclic HPMPC; Cyclic cidofovir; Cidofovir prodrug, Gilead; GS-504 analog; GS-930
Drug Type	Small molecular drug
Indication	Viral infections [ICD9: 054.0, 054.1, 054.2, 054.3, 075, 771.2, 052, 053; ICD10:B01, B02, A60, B00, B27, G05.1, P35.2]		Discontinued in Phase 1	[545808]
Company	Gilead Sciences Inc
Structure		Download 2D MOL 3D MOL
Formula	C8H12N3O5P
Canonical SMILES	n1c(=O)n(ccc1N)C[C@H]1OCP(=O)(OC1)O
CAS Number	CAS 127757-45-3
PubChem Compound ID	122873
Target and Pathway
Target(s)	DNA polymerase	Target Info	Modulator	[544014]
References
Ref 545808	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004825)
Ref 544014	Conversion of 1-[((S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl]cytosine to cidofovir by an intracellular cyclic CMP phosphodiesterase.. Antimicrob Agents Chemother. 1997 March; 41(3): 641-646.

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