Drug General Information
Drug ID	D0I7FI
Former ID	DNC002702
Drug Name	5-AMINO-NAPHTALENE-2-MONOSULFONATE
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[551374]
Structure		Download 2D MOL 3D MOL
Formula	C10H9NO3S
PubChem Compound ID	8408
Target and Pathway
Target(s)	Heparin-binding growth factor1	Target Info	Inhibitor	[551374]
KEGG Pathway	MAPK signaling pathway
	Ras signaling pathway
	Rap1 signaling pathway
	PI3K-Akt signaling pathway
	Hippo signaling pathway
	Regulation of actin cytoskeleton
	Pathways in cancer
	Melanoma
PANTHER Pathway	Angiogenesis
	FGF signaling pathway
Pathway Interaction Database	FGF signaling pathway
Reactome	PI3K Cascade
	PIP3 activates AKT signaling
	FGFR4 ligand binding and activation
	FGFR3c ligand binding and activation
	FGFR2c ligand binding and activation
	FGFR2b ligand binding and activation
	FGFR3 mutant receptor activation
	Activated point mutants of FGFR2
	Constitutive Signaling by Aberrant PI3K in Cancer
	Phospholipase C-mediated cascade: FGFR1
	Phospholipase C-mediated cascade
	Phospholipase C-mediated cascade
	Phospholipase C-mediated cascade
	SHC-mediated cascade:FGFR1
	PI-3K cascade:FGFR1
	FRS-mediated FGFR1 signaling
	PI-3K cascade:FGFR2
	SHC-mediated cascade:FGFR2
	FRS-mediated FGFR2 signaling
	SHC-mediated cascade:FGFR3
	FRS-mediated FGFR3 signaling
	PI-3K cascade:FGFR3
	FRS-mediated FGFR4 signaling
	SHC-mediated cascade:FGFR4
	PI-3K cascade:FGFR4
	Negative regulation of FGFR1 signaling
	Negative regulation of FGFR2 signaling
	Negative regulation of FGFR3 signaling
	Negative regulation of FGFR4 signaling
	RAF/MAP kinase cascade
WikiPathways	Regulation of Actin Cytoskeleton
	Differentiation Pathway
	Hair Follicle Development: Organogenesis (Part 2 of 3)
	Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
	PIP3 activates AKT signaling
	Integrated Pancreatic Cancer Pathway
	Signaling by FGFR
References
Ref 551374	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
Ref 551374	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.

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