Drug Information
Drug General Information | |||||
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Drug ID |
D0I8AF
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Former ID |
DIB019082
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Drug Name |
CCK-8
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Synonyms |
cholecystokinin 8; cholecystokinin fragment 26-33 amide (sulphated); CCK-8 (sulphated)
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [543225] | ||
Structure |
Download2D MOL |
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Formula |
C49H62N10O16S3
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InChI |
InChI=1S/C49H62N10O16S3/c1-76-18-16-34(55-47(69)37(58-44(66)32(50)23-41(61)62)21-28-12-14-30(15-13-28)75-78(72,73)74)45(67)53-26-40(60)54-38(22-29-25-52-33-11-7-6-10-31(29)33)48(70)56-35(17-19-77-2)46(68)59-39(24-42(63)64)49(71)57-36(43(51)65)20-27-8-4-3-5-9-27/h3-15,25,32,34-39,52H,16-24,26,50H2,1-2H3,(H2,51,65)(H,53,67)(H,54,60)(H,55,69)(H,56,70)(H,57,71)(H,58,66)(H,59,68)(H,61,62)(H,63,64)(H,72,73,74)/t32-,34-,35-,36-,37-,38-,39-/m0/s1
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InChIKey |
IZTQOLKUZKXIRV-YRVFCXMDSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Cholecystokinin receptor type A | Target Info | Agonist | [530383] | |
Gastrin/cholecystokinin type B receptor | Target Info | Agonist | [533991] | ||
PANTHER Pathway | CCKR signaling map ST | ||||
PathWhiz Pathway | Gastric Acid Production | ||||
References | |||||
Ref 530383 | Development of a class of selective cholecystokinin type B receptor antagonists having potent anxiolytic activity. Proc Natl Acad Sci U S A. 1990 Sep;87(17):6728-32. | ||||
Ref 533991 | Functional characterization of a human brain cholecystokinin-B receptor. A trophic effect of cholecystokinin and gastrin. J Biol Chem. 1993 Aug 25;268(24):18300-5. |
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