Drug General Information
Drug ID	D0J8RS
Former ID	DNC013256
Drug Name	PD-146176
Drug Type	Small molecular drug
Indication	Atherosclerosis [ICD9: 414.0, 440; ICD10:I70]		Terminated	[546784]
Structure		Download 2D MOL 3D MOL
Formula	C15H11NS
Canonical SMILES	C1C2=C(C3=CC=CC=C3S1)NC4=CC=CC=C24
InChI	1S/C15H11NS/c1-3-7-13-10(5-1)12-9-17-14-8-4-2-6-11(14)15(12)16-13/h1-8,16H,9H2
InChIKey	ZGOOPZVQMLHPFM-UHFFFAOYSA-N
PubChem Compound ID	297589
Target and Pathway
Target(s)	Arachidonate 5-lipoxygenase	Target Info	Modulator
BioCyc Pathway	Aspirin-triggered lipoxin biosynthesis
	Resolvin D biosynthesis
	Leukotriene biosynthesis
	Lipoxin biosynthesis
	Aspirin triggered resolvin D biosynthesis
	Aspirin triggered resolvin E biosynthesis
KEGG Pathway	Arachidonic acid metabolism
	Metabolic pathways
	Serotonergic synapse
	Ovarian steroidogenesis
	Toxoplasmosis
NetPath Pathway	IL4 Signaling Pathway
PathWhiz Pathway	Arachidonic Acid Metabolism
WikiPathways	Vitamin D Receptor Pathway
	Arachidonic acid metabolism
	Eicosanoid Synthesis
	Selenium Micronutrient Network
References
Ref 546784	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010267)

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