Drug General Information
Drug ID
D0J9VK
Former ID
DIB014733
Drug Name
CM-156
Synonyms
CM-156; Sigma opioid antagonists (addiction); Sigma opioid antagonists (addiction), University of Mississippi; 2(3H)-benzoxalones and 2(3H)-benzothiazolones (addiction), University of Mississippi
Indication Drug abuse [ICD9: 303-304; ICD10:F10-F19] Investigative [526642], [532713]
Company
University of Mississippi
Structure
Download
2D MOL

3D MOL

Canonical SMILES
C1CN(CCN1C1CCCCC1)CCCCn1c2ccccc2sc1=S
Target and Pathway
Target(s) Sigma(1)-type opioid receptor Target Info Antagonist [526642], [532713]
WikiPathways miR-targeted genes in squamous cell - TarBase
miR-targeted genes in lymphocytes - TarBase
References
Ref 526642Dextromethorphan antagonizes the acute depletion of brain serotonin by p-chloroamphetamine and H75/12 in rats. Brain Res. 1992 Oct 30;594(2):323-6.
Ref 532713Antitussives and substance abuse. Subst Abuse Rehabil. 2013 Nov 6;4:75-82.
Ref 526642Dextromethorphan antagonizes the acute depletion of brain serotonin by p-chloroamphetamine and H75/12 in rats. Brain Res. 1992 Oct 30;594(2):323-6.
Ref 532713Antitussives and substance abuse. Subst Abuse Rehabil. 2013 Nov 6;4:75-82.

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