Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0K0KR
|
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| Former ID |
DNC004937
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| Drug Name |
AR-129330
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [527629] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C25H29BrF3N5O3S
|
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| Canonical SMILES |
CN(C)C1=NC(=NC2=CC=CC=C21)NCC3CCC(CC3)CNS(=O)(=O)C4=C(C<br />=C(C=C4)Br)OC(F)(F)F.Cl
|
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| InChI |
1S/C25H29BrF3N5O3S.ClH/c1-34(2)23-19-5-3-4-6-20(19)32-24(33-23)30-14-16-7-9-17(10-8-16)15-31-38(35,36)22-12-11-18(26)13-21(22)37-25(27,28)29;/h3-6,11-13,16-17,31H,7-10,14-15H2,1-2H3,(H,30,32,33);1H
|
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| InChIKey |
SMEDDEAAKQVMQD-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Melanin-concentrating hormone receptor 1 | Target Info | Inhibitor | [527629] | |
| Alpha-2A adrenergic receptor | Target Info | Inhibitor | [527629] | ||
| Neuropeptide Y receptor 5 | Target Info | Inhibitor | [527629] | ||
| PANTHER Pathway | Alpha adrenergic receptor signaling pathway | ||||
| Reactome | Peptide ligand-binding receptors | ||||
| G alpha (q) signalling events | |||||
| G alpha (i) signalling eventsR-HSA-390696:Adrenoceptors | |||||
| Adrenaline signalling through Alpha-2 adrenergic receptor | |||||
| Adrenaline,noradrenaline inhibits insulin secretion | |||||
| G alpha (i) signalling events | |||||
| G alpha (z) signalling events | |||||
| Surfactant metabolismR-HSA-375276:Peptide ligand-binding receptors | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| GPCR ligand binding | |||||
| GPCR downstream signalingWP58:Monoamine GPCRs | |||||
| Platelet Aggregation (Plug Formation) | |||||
| Integration of energy metabolism | |||||
| GPCR downstream signalingWP455:GPCRs, Class A Rhodopsin-like | |||||
| Peptide GPCRs | |||||
| GPCR downstream signaling | |||||
| References | |||||
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