TTD | Drug: D0LE1F

Drug General Information
Drug ID	D0LE1F
Former ID	DIB018316
Drug Name	[3H]L655708
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[467698]
Structure		Download 2D MOL 3D MOL
Formula	C18H19N3O4
InChI	InChI=1S/C18H19N3O4/c1-3-25-18(23)15-16-14-5-4-8-20(14)17(22)12-9-11(24-2)6-7-13(12)21(16)10-19-15/h6-7,9-10,14H,3-5,8H2,1-2H3
InChIKey	YKYOQIXTECBVBB-UHFFFAOYSA-N
PubChem Compound ID	4203080
Target and Pathway
Target(s)	Gamma-aminobutyric-acid receptor alpha-5 subunit	Target Info	Modulator (allosteric modulator)	[543811]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Retrograde endocannabinoid signaling
	GABAergic synapse
	Morphine addiction
	Nicotine addiction
Reactome	Ligand-gated ion channel transport
Reactome	GABA A receptor activation
WikiPathways	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
WikiPathways	Iron uptake and transport
References
Ref 467698	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4363).
Ref 543811	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 408).

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Drug Information