Drug Information

Drug General Information
Drug ID
D0M0YB
Former ID
DIB010458
Drug Name
BAY 11-42524
Indication Heart failure [ICD9: 428; ICD10:I50] Phase 1 [549544]
Company
Bayer healthcare pharmaceuticals
Target and Pathway
Target(s) Chymase Target Info Inhibitor [525207]
KEGG Pathway Renin-angiotensin system
Reactome Activation of Matrix Metalloproteinases
Metabolism of Angiotensinogen to Angiotensins
WikiPathways ACE Inhibitor Pathway
Metabolism of Angiotensinogen to Angiotensins
References
Ref 549544Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800040276)
Ref 525207ClinicalTrials.gov (NCT02452515) A Single-blind Pilot Study to Investigate Safety and Tolerability of the Chymase Inhibitor BAY1142524 in Clinically Stable Patients With Left-ventricular Dysfunction.

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