Drug General Information
Drug ID	D0M2HC
Former ID	DNC010838
Drug Name	4-(2-(4-Methylphenylamino)ethyl)-1H-imidazole
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530846]
Structure		Download 2D MOL 3D MOL
Formula	C12H15N3
Canonical SMILES	CC1=CC=C(C=C1)NCCC2=CN=CN2
InChI	1S/C12H15N3/c1-10-2-4-11(5-3-10)14-7-6-12-8-13-9-15-12/h2-5,8-9,14H,6-7H2,1H3,(H,13,15)
InChIKey	OOTAMYWJHGNDAH-UHFFFAOYSA-N
PubChem Compound ID	46222043
Target and Pathway
Target(s)	Histamine H3 receptor	Target Info	Inhibitor	[530846]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Histamine receptors
	G alpha (i) signalling events
WikiPathways	Monoamine Transport
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 530846	J Med Chem. 2010 May 13;53(9):3840-4.Role of hydrophobic substituents on the terminal nitrogen of histamine in receptor binding and agonist activity: development of an orally active histamine type 3 receptor agonist and evaluation of its antistress activity in mice.
Ref 530846	J Med Chem. 2010 May 13;53(9):3840-4.Role of hydrophobic substituents on the terminal nitrogen of histamine in receptor binding and agonist activity: development of an orally active histamine type 3 receptor agonist and evaluation of its antistress activity in mice.

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