Drug Information

Drug General Information
Drug ID
D0M2JA
Former ID
DIB000068
Drug Name
ACP-106
Synonyms
5-HT2A inverse agonists (CNS disorders/sleep disorders), ACADIA
Indication Central nervous system disease [ICD10:G00-G99] Investigative [526792]
Company
ACADIA Pharmaceuticals Inc
Target and Pathway
Target(s) 5-hydroxytryptamine 2A receptor Target Info Agonist [526792]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Serotonergic synapse
Inflammatory mediator regulation of TRP channels
PANTHER Pathway 5HT2 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (q) signalling events
WikiPathways Serotonin Receptor 2 and STAT3 Signaling
Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
SIDS Susceptibility Pathways
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 526792Pharmacological profile of the new potent neuroleptic ocaperidone (R 79,598). J Pharmacol Exp Ther. 1992 Jan;260(1):146-59.
Ref 526792Pharmacological profile of the new potent neuroleptic ocaperidone (R 79,598). J Pharmacol Exp Ther. 1992 Jan;260(1):146-59.

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