Drug Information

Drug General Information
Drug ID
D0M3HZ
Former ID
DIB018924
Drug Name
AZ13483342
Synonyms
AZ 13483342; AZ-13483342
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528866]
Structure
Download
2D MOL
Formula
C19H23N3OS
InChI
InChI=1S/C19H23N3OS/c1-14-10-19(22-18-5-4-16(23-2)11-17(14)18)21-8-3-7-20-12-15-6-9-24-13-15/h4-6,9-11,13,20H,3,7-8,12H2,1-2H3,(H,21,22)
InChIKey
ZDKZIFSAJUTJSK-UHFFFAOYSA-N
PubChem Compound ID
9927967
PubChem Substance ID
14900359, 24203974, 80873387, 103551549, 104089255, 223366068, 224057379, 231716944, 245489711
Target and Pathway
Target(s) Melanin-concentrating hormone receptor 1 Target Info Antagonist [528866]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 528866Discovery of cyclopentane- and cyclohexane-trans-1,3-diamines as potent melanin-concentrating hormone receptor 1 antagonists. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4232-41. Epub 2007 May 17.
Ref 528866Discovery of cyclopentane- and cyclohexane-trans-1,3-diamines as potent melanin-concentrating hormone receptor 1 antagonists. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4232-41. Epub 2007 May 17.

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