Drug General Information
Drug ID
D0M4JK
Former ID
DIB013830
Drug Name
UCB-2892
Synonyms
H3 antagonist (cognitive disorders); UCB-2892; H3 antagonist (cognitive disorders), UCB
Indication Cognitive disorders [ICD9: 290-294, 294.0, 780.09, 780.9, 780.93; ICD10:F01-F07, F04, F05, R41.3] Investigative [543673]
Company
UCB SA
Structure
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2D MOL

3D MOL

Canonical SMILES
N1(C(=O)CC[C@H]1CN1CCCC1)c1ccc(cc1)OCCCN1[C@H](CCC1)C
Target and Pathway
Target(s) Histamine H3 receptor Target Info Antagonist [543673]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Histamine receptors
G alpha (i) signalling events
WikiPathways Monoamine Transport
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 543673(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 264).
Ref 543673(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 264).

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